Comparative effectiveness medicines research cannot assess efficacy

An Approach to Assess Generalizability in Comparative Effectiveness Research

Table B5: Results of the placebo test (figures are for the incidence rate ratio for the trial controls vs. non-participants and 95% confidence intervals, except for mortality, where figures are for the odds ratio) Generalized linear modeling Time series Emergency admissions per head Primary care contacts per head 0.92 (0.87, 0.97) 0.92 (0.87, 0.98) Mortality 2.17 (1.16, 4.08) n/a Note: Time ser...

The hazards of comparative effectiveness when we cannot effectively compare.

According to the Agency for Health Care Research and Quality, “comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options” (1). The data derived from clinical registries play an important role in assessing the effectiveness and appropriateness of various treatments, and their use i...

P11-Why Cannot We Assess Aptitude in Iran

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CEPAC and comparative effectiveness research.

Methods in comparative effectiveness research.

Comparative effectiveness research (CER) seeks to assist consumers, clinicians, purchasers, and policy makers to make informed decisions to improve health care at both the individual and population levels. CER includes evidence generation and evidence synthesis. Randomized controlled trials are central to CER because of the lack of selection bias, with the recent development of adaptive and pra...